all the world's a stage...
I'm a Computer Science undergraduate in my final year studying at Reading University. I like music, movies, photography, reading and if I can ever get around to it, writing. Also a fan of horror, sci-fi and fantasy so there's plenty of re/blogging on those areas.
I write gig/event reviews at From The Pit
Currently conducting my Serotonin Experiment in a last ditch attempt to hopefully alleviate the symptoms of CFS/ME.
Elsewhere on the web:
Many tweaks to this and web presence in general in the pipeline... when I get around to it.
Weekly Top Artists (via Last.fm):
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poor doctor
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Doctor Who Season 6: A Skit
#note: if you loved series 6 don’t watch it #you might get...
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friend: 10 people have asked to be my valentine
me: sometimes i meow at cats and they meow back -
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this will forever be one of my favourite lines that Ten ever said
that awkward moment when the doctor quotes...
For the full story behind this, read this.
Day 2: Monday 26th September 2011
Second dose this morning. I’ve been trying to work out whether yesterday’s apparent positive effects were indeed due to this sertraline that I’ve started taking. The scientist in me is mindful that it could have been a placebo effect- that I felt better simply because I had started taking something rather than due to any pharmacological effect. I doubt it though because my attitude was just that I would try it to see what would happen, without any preconceptions. I don’t know, is it possible to believe something and not realise that you believe it?
As it turns out, peak plasma concentrations of sertraline occurs anywhere between 4-8.4 hours - that’s combining the figures from Wikipedia (4-6) and other sources (4.5-8.4). That’s how long it takes for sertraline to reach its maximum concentration in circulation. So at 2-3 hours when I began experiencing nausea and higher temperature, I think it must indeed have been the sertraline starting to kick in.
Didn’t experience any side effects today so perhaps it was just the initial mild shock to the system of having slightly higher (read: normal?) serotonin levels. I’m guessing yesterday’s adverse reaction was just an initial reaction to the new drug entering my system. As sertraline has a half-life of 26 hours, this morning I will have had about half of yesterday morning’s dose still in circulation. So today’s dose was just to top up the amount of sertraline I have in circulation.
What might have been another side effect is that I had a little trouble sleeping last night but that’s nothing new. There are times when I frequently have trouble sleeping anyway.
